Resources for the Comprehensive Geriatric Assessment based
Proactive and Personalised Primary Care of the Elderly

Frailty

  • Barzilay JI, 2007

Barzilay JI; Blaum C, Moore T, et al. (2007). "Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study.". Arch Intern Med 167: 635–641.

view/access

 

  • Blaum CS, 2005

Blaum CS; Xue QL, Michelon E, Semba RD, Fried LP (Jun 2005). "The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies". J Am Geriatr Soc. 53 (6): 927–34.
view/access

 

  • Cappola AR, 2009

Cappola AR; Xue QL, Fried LP. (Feb 2009). "Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies.". J Gerontol A Biol Sci Med Sci. 64 (2): 243–8.

view/access

 

  • Cesari M, 2014

Matteo Cesari, Giovanni Gambassi, Gabor Abellan van Kan, Bruno Vellas

The frailty phenotype and the frailty index: different instruments for different purposes

Age Ageing (2014) 43 (1): 10-12.

view/access

 

  • Chaves PH, 2005

Chaves PH; Semba RD, Leng SX, Woodman RC, Ferrucci L, Guralnik JM, Fried LP. (Jun 2005). "Impact of anemia and cardiovascular disease on frailty status of community-dwelling older women: the Women's Health and Aging Studies I and II". J Gerontol A Biol Sci Med Sci 60 (6): 729–35.

view/access

 

  • Chaves PH, 2008

Chaves PH; Varadhan R, Lipsitz LA, Stein PK, Windham BG, Tian J, Fleisher LA, Guralnik JM, Fried LP. (Sep 2008). "Physiological complexity underlying heart rate dynamics and frailty status in community-dwelling older women.". J Am Geriatr Soc. 56 (9): 1698–703.

view/access

 

 

  • Ferrucci L, 2002

Ferrucci Luigi; Penninx BW, Volpato S, et al. (2002). "Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels.". J Am Geriatr Soc 50: 1947–54.

http://www.ncbi.nlm.nih.gov/pubmed/12473005?dopt=Abstract

view/access

 

  • Fried LP, 2004

Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004;59:255-63.

view/access

 

  • Fried LP, 2009

Fried, LP; Xue QL, Cappola AR, Ferrucci L, Chaves P, Varadhan R, Guralnik JM, Leng SX, Semba RD, Walston JD, Blaum CS, Bandeen-Roche K (Oct 2009). "Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment". J Gerontol A Biol Sci Med Sci 64 (10): 1049–57.

view/access

 

  • Koller K, 2013

Katalin Koller, Kenneth Rockwood. Frailty in older adults: Implications for end-of-life care. Cleveland Clinic Journal of Medicine March 2013 vol. 80 3 168-174

view/access

 

  • Kulminski AM, 2006

Kulminski A, Yashin A, Ukraintseva S, et al. Accumulation of health disorders as a systemic measure of aging: findings from the NLTCS data. Mech Ageing Dev 2006; 127:840–848

view/access

 

  • Kulminski AM, 2008

Kulminski AM, Ukraintseva SV, Kulminskaya IV, Arbeev KG, Land K, Yashin AI. Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J Am Geriatr Soc 2008; 56:898–903.

view/access

 

  • Morley JE, 2013

Morley JE, Vellas B, van Kan GA, et al. Frailty consensus: a call to action. J Am Med Dir Assoc 2013;14:392-7.                view/access

 

  • Rockwood K, 1994

Rockwood K, Fox RA, Stolee P, Robertson D, Beattie BL (1994) Frailty in elderly people: an evolving concept. CMAJ, 150, 489–95.

view/access

 

  • Rockwood K, 2010

Rockwood K, Rockwood MR, Mitnitski A. Physiological redundancy in older adults in relation to the change with age in the slope of a frailty index. J Am Geriatr Soc 2010; 58:318–323.

view/access

 

  • Rockwood K, 2011

Rockwood K, Mitnitski A. Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin Geriatr Med 2011;27:17-26.

view/access

 

  • Rockwood K, 2012

Rockwood K, Mitnitski A. How might deficit accumulation give rise to frailty? J Frailty Aging 2012; 1: 8–12.

view/access

 

  • Rodríguez-Mañas L, 2013

Rodríguez-Mañas L, Féart C, Mann G, et al. Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci 2013;68:62-7.

view/access

 

  • Rolfson DB, 2006

Rolfson, D.B., Majumdar, S.R., Tsuyuki, R.T., Tahir, A., Rockwood, K. Validity and reliability of the Edmonton Frail Scale. Age Ageing. 2006;35:526–529.

view/access

 

  • Roy CN, 2011

Roy, CN (Feb 2011). "Anemia in frailty.". Clin Geriatr Med. 27 (1): 67–78.

view/access

 

  • Semba RD, 2007

Semba, Richard D.; Ferrucci L, Sun K, Walston J, Varadhan R, Guralnik JM, Fried LP. (Dec 2007). "Oxidative stress and severe walking disability among older women.". Am J Med. 120 (12): 1084–9.

view/access

 

  • Shardell M, 2009

Shardell M; Hicks GE, Miller RR, Kritchevsky S, Andersen D, Bandinelli S, Cherubini A, Ferrucci L (Jan 2009). "Association of low vitamin D levels with the frailty syndrome in men and women". J Gerontol A Biol Sci Med Sci 64 (1): 69–75.

view/access

 

  • Subra J, 2012

Subra J, Gillette-Guyonnet S, Cesari M, Oustric S, Vellas B. The integration of frailty into clinical practice: preliminary results from the gérontopôle. J Nutr Health Aging 2012;16:714-20.            

view/access

 

  • Varadhan R, 2009

Varadhan, R; Chaves PH, Lipsitz LA, Stein PK, Tian J, Windham BG, Berger RD, Fried LP. (Jun 2009). "Frailty and impaired cardiac autonomic control: new insights from principal components aggregation of traditional heart rate variability indices.". J Gerontol A Biol Sci Med Sci. 64 (6): 682–7.                                                                                     

view/access

 

  • Walston J, 2002

Walston, J; McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, Gottdiener J, Fried LP; Cardiovascular Health Study (Nov 2002). "Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study". Arch Intern Med 162 (20): 2333–2341.                                           

view/access

 

  • Wou F, 2013

Wou F, Gladman JR, Bradshaw L, Franklin M, Edmans J, Conroy SP. The predictive properties of frailty-rating scales in the acute medical unit. Age Ageing 2013; 42: 776–81.

view/access

 

  • Xue QL, 2008

Xue QL; Fried LP, Glass TA, Laffan A, Chaves PH (Jan 2008). "Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I". Am J Epidemiol. 167 (2): 240–8.

view/access

 

  • Yao X, 2011

Yao X; Li H, Leng SX. (2011). "Inflammation and immune system alterations in frailty.". Clin Geriatr Med. 27 (1): 79–87.

http://www.ncbi.nlm.nih.gov/pubmed/21093724

view/access